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September 19, 2000Circulation308 citations

Physical Activity and Mortality in Older Men With Diagnosed Coronary Heart Disease

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SWS. Goya WannametheeASA. G. ShaperMWMary Walker

Key Result

Light physical activity in men with established CHD significantly lowered all-cause mortality risk compared to being inactive or occasionally active (RR 0.42; 95% CI 0.25-0.71).

Study Design

Type

Cohort (n=772)

Multicenter

Yes

Structured PICO

Does physical activity reduce all-cause mortality in older men with established coronary heart disease?

P
Population
772 men with established coronary heart disease (myocardial infarction or angina), mean age 63 years, from general practices in 24 British towns.
I
Intervention
Physical activity (light, moderate, or moderately vigorous/vigorous, including recreational activity, gardening, and regular walking)
C
Comparator
Inactive or occasionally active (sedentary)
O
Outcome
All-cause mortality at 5 years follow-uphard clinical

Light or moderate physical activity, including regular walking and gardening, significantly reduces all-cause mortality in older men with established coronary heart disease.

Main Result

Effect estimate: RR 0.42 (95% CI 0.25-0.71)

Abstract

BACKGROUND: We have studied the relations between physical activity, types of physical activity, and changes in physical activity and all-cause mortality in men with established coronary heart disease (CHD). METHODS AND RESULTS: In 1992, 12 to 14 years after the initial screening (Q1) of 7735 men 40 to 59 years of age from general practices in 24 British towns, 5934 (91% of available survivors, mean age 63 years) provided further information on physical activity (Q92) and were followed up for 5 years; 963 had a physician's diagnosis of CHD (myocardial infarction or angina). After exclusions, there were 772 men with established CHD, 131 of whom died of all causes. The lowest risks for all-cause and cardiovascular mortality were seen in light and moderate activity groups (adjusted relative risk compared with inactive/occasionally active: light, 0.42 (0.25, 0.71); moderate, 0.47 (0.24, 0.92); and moderately vigorous/vigorous, 0.63 (0.39, 1.03). Recreational activity of >/=4 hours per weekend, moderate or heavy gardening, and regular walking (>40 min/d) were all associated with a significant reduction in all-cause mortality. Nonsporting activity was more beneficial than sporting activities. Men sedentary at Q1 who began at least light activity by Q92 showed lower mortality rates on follow-up than those who remained sedentary (relative risk 0.58, 95% CI 0.33 to 1.03; P:=0.06). CONCLUSIONS: Light or moderate activity in men with established CHD is associated with a significantly lower risk of all-cause mortality. Regular walking and moderate or heavy gardening were sufficient to achieve this benefit.

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Cite This Study

Wannamethee et al. (2000) conducted a cohort in Coronary heart disease (n=772). Physical activity vs. Inactive/occasionally active was evaluated on All-cause mortality (RR 0.42, 95% CI 0.25-0.71). Light physical activity in men with established CHD significantly lowered all-cause mortality risk compared to being inactive or occasionally active (RR 0.42; 95% CI 0.25-0.71).

synapsesocial.com/papers/6a0d6e776e03bc61cb09c2d1https://doi.org/10.1161/01.cir.102.12.1358
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