PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
July 1, 1976Stroke270 citationsOpen Access

Components of blood pressure and risk of atherothrombotic brain infarction: the Framingham study.

View Full Paper
WKWilliam B. KannelTDThomas R. DawberPSPaul D. Sorlie

Key Result

Hypertension strongly predicted atherothrombotic brain infarction, which developed seven times more often in hypertensive versus normotensive patients over 18 years of follow-up.

Key Points

  • The study aims to examine the relationship between components of blood pressure and the risk of atherothrombotic brain infarction.
  • Analyzed data from the Framingham cohort of 5,209 participants over 18 years of follow-up.
  • Compared incidence rates of atherothrombotic brain infarction (ABI) between hypertensive and normotensive patients.
  • Hypertensive patients developed atherothrombotic brain infarction seven times more often than normotensive patients.
  • The risk of ABI was proportional to blood pressure across its range.

Study Design

Type

Cohort (n=5,209)

Structured PICO

Does hypertension increase the risk of atherothrombotic brain infarction in men and women?

P
Population
5,209 men and women in the Framingham cohort
I
Intervention
Hypertension (elevated blood pressure)
C
Comparator
Normotension
O
Outcome
Atherothrombotic brain infarction (ABI)hard clinical

Hypertension is a powerful precursor to atherothrombotic brain infarction, increasing the risk seven-fold compared to normotension over an 18-year period.

Main Result

Effect estimate: RR 7

Abstract

From a study of the evolution of atherothrombotic brain infarction (ABI) in the Framingham cohort of 5,209 men and women over 18 years of follow-up, it has been ascertained that hypertensionis the most common and most powerful precursor. Atherothrombotic brain infarction developed in hypertensive patients seven times more often than in normotensive patients, and the risk was proportional to the blood pressure throughout its range.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Kannel et al. (1976) conducted a cohort in Atherothrombotic brain infarction (n=5,209). Hypertension vs. Normotension was evaluated on Atherothrombotic brain infarction (RR 7). Hypertension strongly predicted atherothrombotic brain infarction, which developed seven times more often in hypertensive versus normotensive patients over 18 years of follow-up.

synapsesocial.com/papers/6a0dac726e03bc61cb09ddb7https://doi.org/10.1161/01.str.7.4.327
Ask AI
Helpful
Bookmark
Share
View Full Paper