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May 9, 2019BMC Public Health116 citationsOpen Access

Prevalence and predictors of depression among hemodialysis patients: a prospective follow-up study

AKAmjad KhanAKAmer Hayat KhanAAAzreen Syazril Adnan

Key Result

Treatment at non-governmental organization hemodialysis centers was significantly associated with a lower prevalence of depression at the 6-month final visit (OR 0.347).

Study Design

Type

Observational (n=220)

Multicenter

Yes

Structured PICO

P
Population
220 confirmed hypertensive hemodialysis patients. Excluded: patients with physical and/or cognitive limitations preventing them from answering questions.
O
Outcome
Prevalence and predictors of depression assessed using the HADS questionnairepatient reported

Depression is highly prevalent and increases over time among hypertensive hemodialysis patients, though treatment at NGO-run centers is associated with a lower risk.

Main Result

Effect estimate: OR 0.347 (95% CI 0.127-0.949)

p-value: p=0.039

Limitations

  • Limited to only 6 months follow up
  • Did not correlate the depression scores of the same individuals assessed multiple times, requiring separate analysis interpretation
  • Needs a larger sample size and longer follow-up time to confirm findings

Abstract

BACKGROUND: Even though depression is one of the most common psychiatric disorders, it is under-recognized in hemodialysis (HD) patients. Existing literature does not provide enough information on evaluation of predictors of depression among HD patients. The objective of the current study was to determine the prevalence and predictors of depression among HD patients. METHODS: A multicenter prospective follow-up study. All eligible confirmed hypertensive HD patients who were consecutively enrolled for treatment at the study sites were included in the current study. HADS questionnaire was used to assess the depression level among study participants. Patients with physical and/or cognitive limitations that prevent them from being able to answer questions were excluded. RESULTS: Two hundred twenty patients were judged eligible and completed questionnaire at the baseline visit. Subsequently, 216 and 213 patients completed questionnaire on second and final follow up respectively. The prevalence of depression among patients at baseline, 2nd visit and final visit was 71.3, 78.2 and 84.9% respectively. The results of regression analysis showed that treatment given to patients at non-governmental organizations (NGO's) running HD centers (OR = 0.347, p-value = 0.039) had statistically significant association with prevalence of depression at final visit. CONCLUSIONS: Depression was prevalent in the current study participants. Negative association observed between depression and hemodialysis therapy at NGO's running centers signifies patients' satisfaction and better depression management practices at these centers.

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Cite This Study

Khan et al. (2019) conducted an observational in Hemodialysis with hypertension (n=220). Treatment at non-governmental organization (NGO) hemodialysis centers vs. Private or governmental hemodialysis centers was evaluated on Prevalence of depression at final visit (OR 0.347, 95% CI 0.127-0.949, p=0.039). Treatment at non-governmental organization hemodialysis centers was significantly associated with a lower prevalence of depression at the 6-month final visit (OR 0.347).

synapsesocial.com/papers/6a0e1f20e56f987c96d08c7ehttps://doi.org/10.1186/s12889-019-6796-z
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