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August 20, 1982JAMA114 citations

Catheter-induced ablation of the atrioventricular junction to control refractory supraventricular arrhythmias

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MSMelvin M. Scheinman

Key Result

Catheter-induced ablation of the atrioventricular junction using DC shocks produced complete AV block in 100% (5/5) of patients with refractory supraventricular tachycardia.

Key Points

  • To evaluate the effectiveness and safety of catheter-induced ablation in controlling refractory supraventricular arrhythmias.
  • Five patients underwent catheter ablation involving DC shocks to the His bundle.
  • Patients had a history of refractory supraventricular tachycardia resistant to drugs.
  • Follow-up intervals ranged from four to 12 months post-procedure.
  • All patients achieved complete atrioventricular block.
  • One patient died suddenly six weeks after treatment.
  • Mild elevations in creatine phosphokinase MB were observed without hemodynamic evidence of tricuspid insufficiency.

Study Design

Type

Case Report (n=5)

Structured PICO

Does catheter-induced ablation of the AV junction using DC shocks produce complete AV block in patients with refractory supraventricular tachycardia?

P
Population
5 patients with recurrent bouts of supraventricular tachycardia resistant or intolerant to both conventional and experimental drugs
I
Intervention
Delivery of DC shocks to an electrode catheter positioned adjacent to the His bundle (catheter-induced ablation of the atrioventricular junction)
O
Outcome
Complete atrioventricular (AV) blockhard clinical

Catheter-induced DC shock ablation of the His bundle successfully produced complete AV block in patients with refractory supraventricular tachycardia, demonstrating early feasibility of a percutaneous alternative to open-heart surgical ablation.

Abstract

Five patients with recurrent bouts of supraventricular tachycardia proved resistant or became intolerant of both conventional and experimental drugs. These patients were subjected to a new procedure involving delivery of DC shocks to an electrode catheter positioned adjacent to the His bundle. Complete atrioventricular (AV) block was produced in all, one patient died suddenly six weeks after shock therapy, and the remainder had complete AV block with follow-up intervals ranging from four to 12 months. Shock therapy was associated with mild elevations of creatine phosphokinase MB (31± 18 units), but there was no hemodynamic evidence of tricuspid insufficiency. If this new technique proves safe and effective, it should supplant the need for open heart surgical procedures for His-bundle ablation. (JAMA1982;248:851-855)

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Cite This Study

Melvin M. Scheinman (1982) conducted a case report in Refractory supraventricular tachycardia (n=5). Catheter-induced ablation of the atrioventricular junction (DC shocks) was evaluated on Complete atrioventricular (AV) block. Catheter-induced ablation of the atrioventricular junction using DC shocks produced complete AV block in 100% (5/5) of patients with refractory supraventricular tachycardia.

synapsesocial.com/papers/6a0ea97353f874f2b2229cfahttps://doi.org/10.1001/jama.248.7.851
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