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December 1, 1975Biometrics515 citations

394: The Analysis of Binary Responses from Toxicological Experiments Involving Reproduction and Teratogenicity

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DWDavid A. Williams

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Abstract

This paper describes a parametric method for analyzing binary response data from completely randomized experiments in which the experimental units are animal litters. Responses within a litter are assumed to form a set of Bernoulli trials whose success probability varies between litters in the same treatment group according to a two parameter beta distribution. The parameters of the beta distribution for each treatment are estimated by maximum likelihood and treatment differences are tested by asymptotic likelihood ratio tests.

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David A. Williams (1975) studied this question.

synapsesocial.com/papers/6a0eb18ea14f152feaf9b70dhttps://doi.org/10.2307/2529820
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