No prior myocardial infarction (OR 3.048), female gender (OR 1.978), and age were independent risk factors for normal LV ejection fraction in older patients with congestive heart failure.
Observational (n=572)
No
In older patients with CHF, normal LVEF (≥50%) is common (50%) and independently associated with older age, female gender, and absence of prior myocardial infarction.
Effect estimate: OR 1.978
Absolute Event Rate: 56% vs 37%
p-value: p=0.0004
Study objectives To investigate in older patients with congestive heart failure (CHF) associated with prior myocardial infarction or hypertension the relationship between normal left ventricular (LV) ejection fraction and age, gender, hypertension, prior myocardial infarction, and atrial fibrillation. Design A prospective study was performed in 572 older patients (age >60 years) with CHF associated with prior myocardial infarction or hypertension and technically adequate two-dimensional echocardiograms for measuring LV ejection fraction. Setting A long-term health-care facility. Patients One hundred seventy-seven men and 395 women, mean age 82±8 years, with CHF associated with prior myocardial infarction or hypertension. Measurements and results Normal LV ejection fraction (≥50%) occurred in 66 of 177 men (37%) and in 221 of 395 women (56%) (p 60 years) with CHF associated with prior myocardial infarction or hypertension and technically adequate two-dimensional echocardiograms for measuring LV ejection fraction. A long-term health-care facility. One hundred seventy-seven men and 395 women, mean age 82±8 years, with CHF associated with prior myocardial infarction or hypertension. Normal LV ejection fraction (≥50%) occurred in 66 of 177 men (37%) and in 221 of 395 women (56%) (p <0.0001). Multiple logistic regression analysis showed that independent risk factors for normal LV ejection fraction in patients with CHF were no prior myocardial infarction (p=0.0001; odds ratio=3.048), female gender (p=0.0004; odds ratio=1.978), and age (p=0.016; odds ratio=1.029). Normal LV ejection fraction occurred in 50% of 572 older patients with CHF associated with prior myocardial infarction or hypertension. Independent risk factors for normal LV ejection fraction in patients with CHF were no prior myocardial infarction, female gender, and age.
Aronow et al. (1998) conducted an observational in Congestive heart failure associated with prior myocardial infarction or hypertension (n=572). Risk factors (no prior MI, female gender, age) was evaluated on Normal LV ejection fraction (≥50%) (OR 1.978, p=0.0004). No prior myocardial infarction (OR 3.048), female gender (OR 1.978), and age were independent risk factors for normal LV ejection fraction in older patients with congestive heart failure.