Labelled magnetic resonance imaging using SPAMM showed radial shortening was twice as great in the endocardium (20.4%) than in the epicardium (10.2%) in normal volunteers.
Observational (n=5)
SPAMM MRI is a feasible technique for assessing regional left ventricular function, with radial shortening appearing as a promising marker.
Absolute Event Rate: 20.4% vs 10.2%
A technique for assessing regional left ventricular function using magnetic resonance imaging is described. Spatial modulation of magnetization (SPAMM) is effected immediately before images are obtained at various intervals during the cardiac cycle using a modified field echo even rephasing technique (FEER). By performing such modulation in two planes, a grid pattern of labelling can be produced across the image. On the resulting labelled short axis images of the left ventricle, the systolic increase in thickness (thickening) and decrease in length (shortening) of different regions of myocardium can then be measured. The findings in five normal volunteers are presented. Radial shortening was twice as great in the endocardium (mean 20.4%, standard deviation (SD) 5.7) than in the epicardium (mean 10.2%, SD 5.5) and appears to offer more promise as a marker of regional function than simple thickening (mean 9.8%, SD 13.6).
Buchalter et al. (1991) conducted an observational in Normal volunteers (n=5). Labelled magnetic resonance imaging (SPAMM) was evaluated on Radial shortening. Labelled magnetic resonance imaging using SPAMM showed radial shortening was twice as great in the endocardium (20.4%) than in the epicardium (10.2%) in normal volunteers.