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March 1, 1975Archives of Internal Medicine67 citations

Pathophysiology of Ventricular Tachycardia in Man

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HWHein J.J. Wellens

Key Result

Chronic recurrent ventricular tachycardia is driven by a reentry mechanism, while ventricular tachycardia within 24 hours of myocardial infarction suggests a focal origin.

Structured PICO

P
Population
Patients with ventricular tachycardia (including chronic recurrent and during the first 24 hours after myocardial infarction)
I
Intervention
Programmed electrical stimulation of the heart
O
Outcome
Mechanisms of arrhythmias (reentry vs focal origin)

The study of ventricular tachycardia mechanisms using programmed electrical stimulation suggests different pathophysiological origins depending on the chronicity and context of the arrhythmia.

Abstract

Programmed electrical stimulation of the heart as a method to study mechanisms of arrthythmias is discussed in patients with ventricular tachycardia. Chronic recurrent ventricular tachycardia seems to be based on a reentry mechanism. Observations in patients with ventricular tachycardia during the first 24 hours after myocardial infarction suggest a focal origin of the arrhythmia.

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Cite This Study

Hein J.J. Wellens (1975) studied this question. Chronic recurrent ventricular tachycardia is driven by a reentry mechanism, while ventricular tachycardia within 24 hours of myocardial infarction suggests a focal origin.

synapsesocial.com/papers/6a0edf82aa1655e5fb22ee60https://doi.org/10.1001/archinte.1975.00330030123012
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