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August 7, 2015Biomedical Optics Express35 citationsOpen Access

Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry

DHDavid HerranzJLJuan Bautista Martí LloretSJSantiago Jiménez‐Valero

Key Result

A novel radiofrequency ablation catheter with integrated polarization-sensitive optical coherence reflectometry successfully enabled real-time monitoring of lesion depth during in-vitro swine myocardium ablation.

Structured PICO

P
Population
in-vitro model of swine myocardium
I
Intervention
novel radiofrequency ablation catheter with integrated custom designed optics for polarization-sensitive optical coherence reflectometry
O
Outcome
optical performance and thermal stability

A novel RF ablation catheter with integrated optical coherence reflectometry demonstrated optical performance and thermal stability in an in-vitro swine myocardium model, potentially enabling real-time lesion depth assessment.

Limitations

  • In-vitro study
  • Current catheter needs extension to have direct imaging in multiple directions to cover the full active volume around the RF electrode for in-vivo procedures

Abstract

A novel radiofrequency ablation catheter has been developed with integrated custom designed optics, enabling real-time monitoring of radiofrequency ablation procedures through polarization-sensitive optical coherence reflectometry. The optics allow for proper tissue illumination through a view-port machined in the catheter tip, thus providing lesion depth control over the RF ablation treatment. The system was verified in an in-vitro model of swine myocardium. Optical performance and thermal stability was confirmed after more than 25 procedures, without any damage to the optical assembly induced by thermal stress or material degradation. The use of this catheter in RF ablation treatments may make possible to assess lesion depth during therapy, thus translating into a reduction of potential complications on the procedure.

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Cite This Study

Herranz et al. (2015) studied Cardiac arrhythmias (Atrial fibrillation). Novel catheter with integrated polarization-sensitive optical coherence reflectometry (PS-OCR) was evaluated on Real-time monitoring of radiofrequency ablation procedures (lesion depth and tissue contact). A novel radiofrequency ablation catheter with integrated polarization-sensitive optical coherence reflectometry successfully enabled real-time monitoring of lesion depth during in-vitro swine myocardium ablation.

synapsesocial.com/papers/6a0eea2fc12540356222c80fhttps://doi.org/10.1364/boe.6.003268
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In vivo intracardiac optical coherence tomography imaging through percutaneous access: toward image-guided radio-frequency ablation2011 · 36 citations
  2. 2Temperature monitoring during radiofrequency catheter ablation of accessory pathways.1992 · 180 citations
  3. 3Radiofrequency catheter ablation of ventricular tachycardia in patients without structural heart disease.1992 · 505 citations
  4. 4Linear Ablation Lesions for Control of Unmappable Ventricular Tachycardia in Patients With Ischemic and Nonischemic Cardiomyopathy2000 · 1,223 citations
  5. 5Effects of Open‐Irrigated Radiofrequency Ablation Catheter Design on Lesion Formation and Complications: In Vitro Comparison of 6 Different Devices2013 · 72 citations