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In the present paper, we study 2-local derivations of infinite-dimensional Lie algebras over a field of characteristic zero. We prove that all 2-local derivations of the Witt algebra as well as of the positive Witt algebra and the classical one-sided Witt algebra are (global) derivations. We also give an example of an infinite-dimensional Lie algebra with a 2-local derivation which is not a derivation.
Ayupov et al. (2019) studied this question.