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May 1, 1988Pacing and Clinical ElectrophysiologyOpen Access

Diagnosis of Atrial Fibrillation Using Electrograms from Chronic Leads: Evaluation of Computer Algorithms

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Why the study?

Do computer algorithms accurately detect atrial fibrillation from chronic pacing leads in dogs?

Population

Dogs with implanted chronic atrial and ventricular leads, recorded in sinus rhythm and induced atrial…

Comparison

Three signal processing methods for detecting… vs Sinus rhythm

Design

Preclinical

Follow-up

up to 55 days following implantation

Key result

Three signal processing algorithms effectively detected atrial fibrillation from chronic pacing leads in dogs, with spectral analysis yielding 100% sensitivity and 95% specificity.

Authors

JJJanice M. JenkinsKNKI HONG NOHAGAlain Guezennec

Discussion

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Member takes

Overview

May support algorithm development from pacing leads; leaves open human translation.

Structured PICO

Do computer algorithms accurately detect atrial fibrillation from chronic pacing leads in dogs?

P
Population
Dogs with implanted chronic atrial and ventricular leads, recorded in sinus rhythm and induced atrial fibrillation
I
Intervention
Three signal processing methods for detecting atrial fibrillation: software recognition of rate with automatic threshold control, amplitude distribution, and frequency spectral analysis
C
Comparator
Sinus rhythm
O
Outcome
Performance in detection of atrial fibrillation (sensitivity and specificity)surrogate

Computer algorithms using amplitude distribution or rate determination can perfectly separate atrial fibrillation from sinus rhythm in chronic pacing leads in a canine model.

Cite This Study

Jenkins et al. (1988) studied Atrial fibrillation. Three detection algorithms (rate, amplitude distribution, frequency spectral analysis) was evaluated on Performance in detection of atrial fibrillation. Three signal processing algorithms effectively detected atrial fibrillation from chronic pacing leads in dogs, with spectral analysis yielding 100% sensitivity and 95% specificity.

synapsesocial.com/papers/6a0f03b22eca052da64804cbhttps://doi.org/10.1111/j.1540-8159.1988.tb04558.x
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