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December 17, 2010Expert Review of Cardiovascular Therapy46 citationsOpen Access

MRI of the left atrium: predicting clinical outcomes in patients with atrial fibrillation

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MDMarcos DaccarettCMChris McGannNANazem Akoum

Key Result

Late gadolinium-enhancement cardiovascular MRI aids in the individualized treatment of atrial fibrillation by stratifying recurrence risk and guiding specific ablation strategies.

Structured PICO

Does late gadolinium-enhancement MRI of the left atrium predict clinical outcomes in patients with atrial fibrillation?

P
Population
Patients with atrial fibrillation
I
Intervention
Late gadolinium-enhancement cardiovascular MRI of the left atrium
O
Outcome
Prediction of clinical outcomes (recurrence after catheter ablation, thromboembolic events)

Late gadolinium-enhancement MRI of the left atrium is a valuable tool for assessing structural remodeling and fibrosis, aiding in the individualized treatment of atrial fibrillation by stratifying recurrence risk and guiding ablation strategies.

Abstract

Atrial fibrillation is a significant public health burden, with clinically, epidemiologically and economically significant repercussions. In the last decade, catheter ablation has provided an improvement in morbidity and quality of life, significantly reducing long-term healthcare costs and avoiding recurrences compared with drug therapy. Despite recent progress in techniques, current catheter ablation success rates fall short of expectations. Late gadolinium-enhancement cardiovascular MRI is a well-established tool to image the myocardium and, most specifically, the left atrium. Unique imaging protocols allow for left atrial structural remodeling and fibrosis assessment, which has been demonstrated to correlate with clinical outcomes after catheter ablation, assessment of the individual's risks of thromboembolic events, and effective imaging of patients with left atrial appendage thrombus. Late gadolinium-enhancement MRI aids in the individualized treatment of atrial fibrillation, stratifying recurrence risk and guiding specific ablation strategies. Real-time MRI offers significant safety and effectiveness profiles that would optimize the invasive treatment of atrial fibrillation.

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Cite This Study

Daccarett et al. (2010) conducted a review in Atrial fibrillation. Late gadolinium-enhancement cardiovascular MRI was evaluated. Late gadolinium-enhancement cardiovascular MRI aids in the individualized treatment of atrial fibrillation by stratifying recurrence risk and guiding specific ablation strategies.

synapsesocial.com/papers/6a0f3cba04e2b0ba896cb937https://doi.org/10.1586/erc.10.177
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