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October 28, 2022Cureus1 citationsOpen Access

Abdominal and Pelvic Computed Tomography for the Diagnosis of ST-Elevation Myocardial Infarction: The Challenges of Acute Coronary Syndrome in Diabetic Patients

BBBlake BriggsEZEdan ZitelnyTZTamir Zitelny

Key Result

An abdominal and pelvic CT scan with IV contrast successfully identified severe hypoattenuation of the left ventricular wall, leading to the diagnosis of an inferior STEMI in a diabetic patient.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 56-year-old female with insulin-dependent type II diabetes mellitus presenting with symptoms of diabetic ketoacidosis (abdominal pain, nausea, vomiting, diarrhea) and no typical ischemic symptoms.
I
Intervention
Computed tomography (CT) of the abdomen and pelvis with IV contrast
O
Outcome
Diagnosis of acute myocardial infarction (inferior STEMI)

Abdominal and pelvic CT with IV contrast can incidentally detect myocardial ischemia in diabetic patients presenting with atypical symptoms, highlighting the need for a low threshold for EKG screening in this high-risk population.

Limitations

  • Single case report
  • CT of the abdomen and pelvis with IV contrast should not be routinely performed or relied upon for the diagnosis of MI
  • No standardized protocols have been developed for detecting ischemia on standard CT
  • No standardized protocols for detecting myocardial ischemia on abdominal CT

Abstract

Diabetes mellitus (DM) is a major independent risk factor for cardiovascular disease. Patients who present with the metabolic emergency of diabetic ketoacidosis (DKA) have similar symptoms of diaphoresis, nausea, emesis, and abdominal pain, which can conceal acute coronary syndrome (ACS). We present a unique case where computed tomography (CT) of the abdomen and pelvis with IV contrast played an integral role in diagnosing an acute myocardial infarction in a patient with no typical ischemic symptoms. A 56-year-old female presented to the emergency department with abdominal pain, nausea, and vomiting. She was suspected of having DKA. Aggressive management was started, including weight-based appropriate IV regular insulin. A CT abdomen and pelvis with IV contrast was performed due to persistent abdomen pain. This demonstrated severe hypoattenuation of the posteroinferior aspect of the left ventricular wall. An EKG was immediately performed and was consistent with an inferior STEMI. The patient was taken to the interventional cardiology suite where they found the culprit lesion to be mid-circumflex with 100% stenosis. This case highlights many important lessons in approaching diabetic patients who are presenting with DKA. DM is associated with cardiac autonomic neuropathy (CAN), a condition that greatly influences perceived chest pain. While little is known about this condition, some manifestations include resting tachycardia, exercise intolerance, orthostatic hypotension, and an increased risk of silent myocardial infarction. Critically, providers must maintain a low threshold to assess for cardiac ischemia in diabetic patients and more readily obtain EKGs in triage as well as during the patient's course in the ED to prevent complications from delayed ACS care.

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Cite This Study

Briggs et al. (2022) conducted a case report in ST-Elevation Myocardial Infarction and Diabetic Ketoacidosis (n=1). Abdominal and Pelvic Computed Tomography with IV contrast was evaluated on Diagnosis of acute myocardial infarction. An abdominal and pelvic CT scan with IV contrast successfully identified severe hypoattenuation of the left ventricular wall, leading to the diagnosis of an inferior STEMI in a diabetic patient.

synapsesocial.com/papers/6a0f4b76b6f5ee04015f9fdfhttps://doi.org/10.7759/cureus.30816
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