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November 10, 2016Acute Medicine & Surgery95 citationsOpen Access

Importance of respiratory rate for the prediction of clinical deterioration after emergency department discharge: a single‐center, case–control study

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KMKatsunori MochizukiRSRyosuke ShintaniKMKotaro Mori

Key Result

An increased respiratory rate prior to emergency department discharge was an independent predictor of clinical deterioration and ED revisit within 2 days (adjusted OR 1.15; 95% CI 1.01-1.29).

Study Design

Type

Case-Control (n=15,724)

Multicenter

No

Structured PICO

Does an increased respiratory rate predict early clinical deterioration after emergency department discharge in adult medical patients?

P
Population
Adult patients with medical conditions discharged from the emergency department, including 170 who revisited with clinical deterioration within 2 days (cases) and a control group, drawn from a total of 15,724 discharged patients.
I
Intervention
Increased respiratory rate at initial ED presentation
C
Comparator
Lower/normal respiratory rate
O
Outcome
Clinical deterioration requiring ED revisit within 2 days of dischargehard clinical

An increased respiratory rate at initial ED presentation is an independent predictor of early clinical deterioration and ED revisit within 2 days of discharge.

Main Result

Effect estimate: adjusted OR 1.15 (95% CI 1.01-1.29)

p-value: p=0.002

Abstract

Aim The purpose of the present study was to investigate the predictors of clinical deterioration soon after emergency department ( ED ) discharge. Methods We undertook a case–control study using the ED database of the Nagano Municipal Hospital (Nagano, Japan) from January 2012 to December 2013. We selected adult patients with medical conditions who revisited the ED with deterioration within 2 days of ED discharge (deterioration group). The deterioration group was compared with a control group. Results During the study period, 15,724 adult medical patients were discharged from the ED . Of these, 170 patients revisited the ED because of clinical deterioration within 2 days. Among the initial vital signs, respiratory rate was less frequently recorded than other vital signs ( P < 0.001 versus all other vital signs in each group). The frequency of recording each vital sign did not differ significantly between the groups. Overall, patients in the deterioration group had significantly higher respiratory rates than those in the control group (21 ± 5/min versus 18 ± 5/min, respectively; P = 0.002). A binary logistic regression analysis revealed that respiratory rate was an independent risk factor for clinical deterioration (unadjusted odds ratio, 1.15; 95% confidence interval, 1.04−1.26; adjusted odds ratio, 1.15; 95% confidence interval, 1.01−1.29). Conclusions An increased respiratory rate is a predictor of early clinical deterioration after ED discharge. Vital signs, especially respiratory rate, should be carefully evaluated when making decisions about patient disposition in the ED .

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Cite This Study

Mochizuki et al. (2016) conducted a case-control in Clinical deterioration after emergency department discharge (n=15,724). Increased respiratory rate vs. Lower respiratory rate was evaluated on Clinical deterioration requiring ED revisit within 2 days of discharge (adjusted OR 1.15, 95% CI 1.01-1.29, p=0.002). An increased respiratory rate prior to emergency department discharge was an independent predictor of clinical deterioration and ED revisit within 2 days (adjusted OR 1.15; 95% CI 1.01-1.29).

synapsesocial.com/papers/6a0f52ec8090e499da5faea7https://doi.org/10.1002/ams2.252
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