Visceral adipose tissue area was the strongest predictor of lipid-lipoprotein profile variables in healthy women, explaining 7% to 48% of the variance (p<=0.0001).
Cross-Sectional (n=66)
Is visceral adipose tissue area a stronger predictor of lipid-lipoprotein alterations than subcutaneous adipose tissue in healthy women?
Visceral adipose tissue area is a stronger correlate of lipid-lipoprotein alterations than subcutaneous adipose tissue in healthy women.
p-value: p=<0.0001
OBJECTIVE: The aim of this study was to compare the relative importance of computed tomography-measured abdominal fat compartment areas, including adipose tissue located posterior to the subcutaneous Fascia, in predicting plasma lipid-lipoprotein alterations. RESEARCH METHODS AND PROCEDURES: Areas of visceral as well as subcutaneous deep and superficial abdominal adipose tissue were measured by computed tomography in a sample of 66 healthy women, ages 37 to 60 years, for whom a detailed lipid-lipoprotein profile was available. RESULTS: Strong significant associations were observed between visceral adipose tissue area and most variables of the lipid-lipoprotein profile (r = -0.25, p or = p < or = 0.0001). DISCUSSION: Although previous studies have generated controversial data as to which abdominal adipose tissue compartment was more closely associated with insulin resistance, our results suggest that visceral adipose tissue area is a stronger correlate of other obesity-related outcomes such as lipid-lipoprotein alterations.
Deschênes et al. (2003) conducted a cross-sectional in Healthy (n=66). Computed tomography-measured abdominal fat compartment areas was evaluated on Plasma lipid-lipoprotein alterations (p=<0.0001). Visceral adipose tissue area was the strongest predictor of lipid-lipoprotein profile variables in healthy women, explaining 7% to 48% of the variance (p<=0.0001).