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June 1, 1977Annual Review of Biochemistry1,311 citations

Biochemical Evolution

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AWAnna WilsonBoston UniversitySCSteven S. CarlsonIowa State UniversityTWThomas J. WhiteUniversity of California, Berkeley

Key Points

  • To explore the Hippo pathway's role in regulating tissue growth and its evolutionary conservation across species.
  • Analyzed the Hippo pathway in Drosophila melanogaster
  • Examined its functions in cell growth and size regulation
  • Utilized comparative studies across different species
  • Demonstrated the significance of the Hippo pathway in tissue growth regulation
  • Identified key biological processes influenced by this signaling cascade
  • Highlighted evolutionary conservation across species

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

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Cite This Study

Wilson et al. (1977) studied this question.

synapsesocial.com/papers/6a0f8ac8d13714ec96fe475fhttps://doi.org/10.1146/annurev.bi.46.070177.003041
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