Anger and aggression were significantly correlated with the severity of carotid atherosclerosis, demonstrating correlations with plaque score of r=0.65 (P<0.01) and r=0.50 (P<0.01), respectively.
Cross-Sectional (n=34)
Do anger and aggression correlate with the severity of carotid atherosclerosis in patients with atherosclerosis risk factors?
Anger and aggression are significantly correlated with the severity of carotid atherosclerosis, suggesting they may be psychosocial risk factors for cerebrovascular disease.
Effect estimate: r = 0.65 (anger), r = 0.50 (aggression)
p-value: p=<0.01
BACKGROUND AND PURPOSE: Although a number of metabolic and psychosocial factors have been identified as coronary risk factors, no studies have evaluated the relation between personality and cerebrovascular disease. The purpose of the present study was to elucidate the relation between the characteristics of anger or aggression and the severity of carotid atherosclerosis on the basis of the findings of B-mode ultrasonography. METHODS: The Cornell Medical Index was used to measure anger in 34 patients with signs of atherosclerosis or at least one of four recognized risk factors for atherosclerosis (hypertension, hypercholesterolemia, diabetes mellitus, and cigarette smoking). The Rosenzweig Picture Frustration Study and Yatabe-Guilford Personality Test were used to evaluate aggression. High-resolution B-mode ultrasonography was performed, and the severity of carotid atherosclerosis was determined by plaque score. The occurrence of risk factors for carotid atherosclerosis was compared among the patients. RESULTS: The correlation of plaque score with one item that endorses anger was r = .65 (P < .01) and with "extrapersistive" in aggression was r = .50 (P < .01). Multivariate analysis identified significant correlations between plaque score and age, hypercholesterolemia, and anger. CONCLUSIONS: Our results suggest that anger and, perhaps, aggression may be risk factors for cerebrovascular disease.
Matsumoto et al. (1993) conducted a cross-sectional in Atherosclerosis or risk factors for atherosclerosis (n=34). Anger and aggression (exposure) was evaluated on Severity of carotid atherosclerosis determined by plaque score (r = 0.65 (anger), r = 0.50 (aggression), p=<0.01). Anger and aggression were significantly correlated with the severity of carotid atherosclerosis, demonstrating correlations with plaque score of r=0.65 (P<0.01) and r=0.50 (P<0.01), respectively.