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November 1, 1961Circulation Research312 citationsOpen Access

Experimental Myocardial Infarction

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ASAndres E. Salazah

Key Result

A low-grade direct electrical current passed through an intraluminal and external electrode circuit consistently induces coronary thrombosis in intact closed-chest dogs.

Structured PICO

P
Population
intact closed-chest dog model
I
Intervention
passage of a low-grade direct electrical current through a circuit including a positive intraluminal electrode in a major coronary branch and a negative external electrode on the chest wall
O
Outcome
induction of coronary thrombosis

Describes a reproducible method for inducing experimental coronary thrombosis in a closed-chest dog model using electrical current.

Abstract

Coronary thrombosis can be consistently induced in the intact closed-chest dog by the passage of a low-grade direct electrical current through a circuit that includes a positive intraluminal electrode in a major coronary branch and a negative external electrode on the chest wall.

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Cite This Study

Andres E. Salazah (1961) studied this question. A low-grade direct electrical current passed through an intraluminal and external electrode circuit consistently induces coronary thrombosis in intact closed-chest dogs.

synapsesocial.com/papers/6a0f9d8dd03631df9ce9cc3dhttps://doi.org/10.1161/01.res.9.6.1351
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