Anatomically guided radiofrequency ablation of the atrial isthmus successfully terminated refractory atrial flutter in 19 of 22 patients (86.4%), with only 2 recurrences over 13 months.
Observational (n=22)
Does anatomically guided radiofrequency ablation terminate atrial flutter and prevent recurrences in patients with refractory atrial flutter?
Anatomically guided radiofrequency ablation of the cavotricuspid isthmus is a feasible and effective treatment for refractory atrial flutter.
BACKGROUND: Previous reports have shown that radiofrequency ablation can terminate atrial flutter and prevent recurrences. However, different methods have been used, and the current experience remains limited. The objective of the present study was to determine the efficacy of radiofrequency ablation of atrial tissue in patients with atrial flutter using an anatomically guided approach. METHODS AND RESULTS: We treated 22 patients aged 30 to 73 years. Atrial flutter was recurrent for a mean of 5 years despite the administration of multiple antiarrhythmic drugs. Radiofrequency current was directed to the atrial isthmus between the inferior vena cava and the tricuspid ring, regardless of the morphology of local electrograms. Radiofrequency energy was applied during typical atrial flutter in 12 patients, atypical atrial flutter in 2 patients, and successively both forms in 8 patients. In 19 patients, atrial flutter abruptly terminated. In 3 patients, atrial flutter persisted despite 37, 48, and 25 applications, respectively. Atrial recordings demonstrated that atrial flutter termination occurred as a consequence of conduction block at the site of radiofrequency energy application, regardless of the type of atrial flutter. The number of applications before termination ranged from 1 to 82 (mean, 32). Atrial flutter could no longer be induced in every case. There were no complications. During a 13-month mean follow-up, atrial flutter recurred in only 2 of the 19 patients who had a successful ablation. Four patients experienced chronic atrial fibrillation, and 2 of them returned to sinus rhythm with antiarrhythmic therapy. CONCLUSIONS: Radiofrequency ablation of atrial flutter using anatomic guidance is feasible and effective. Further experience is needed to delineate its role as an alternative approach to the management of refractory atrial flutter.
Kirkorian et al. (1994) conducted an observational in Atrial flutter (n=22). Anatomically guided radiofrequency ablation was evaluated on Termination of atrial flutter. Anatomically guided radiofrequency ablation of the atrial isthmus successfully terminated refractory atrial flutter in 19 of 22 patients (86.4%), with only 2 recurrences over 13 months.