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November 1, 2023BMJ Open Quality11 citationsOpen Access

Identifying and reducing inappropriate aspirin use in primary care

CBChrista BrookerRCRebekah ComptonTBTerri Babineau

Key Result

An EMR-based educational intervention led to aspirin deprescribing in 29% of older adults, with patients seen by providers having lower odds of continued use (OR 0.87; 95% CI 0.81-0.94).

Study Design

Type

Observational (n=361)

Multicenter

No

Structured PICO

Does an EMR-based chart review and educational intervention increase aspirin de-prescribing in patients aged 70 and older taking aspirin for primary prevention?

P
Population
361 patients aged 70 years and older with aspirin listed on their current medication list, including 145 (40%) taking it for primary prevention of atherosclerotic cardiovascular disease.
I
Intervention
Electronic medical record-based chart review to flag inappropriate aspirin use and an educational intervention based on shared decision-making.
C
Comparator
Patients taking aspirin who were not seen by their healthcare provider.
O
Outcome
Aspirin de-prescribing at 9 months.

An EMR-based chart review and educational intervention effectively facilitated the de-prescribing of inappropriate aspirin for primary prevention in older adults.

Main Result

Effect estimate: OR 0.87 (95% CI 0.81-0.94)

Abstract

OBJECTIVE: Recent studies have called into question the safety of aspirin use for the primary prevention of atherosclerotic cardiovascular disease, particularly in older adults. Therefore, the objectives of this study were to (1) develop a systematic approach to identifying patients aged 70 and older taking aspirin for primary prevention, (2) provide patient and provider education about updated literature and recommendations regarding aspirin safety and (3) evaluate the impact of this intervention on aspirin de-prescribing. DESIGN: This was a quality improvement intervention with prospective, longitudinal follow-up. SETTING: This study was conducted in two family medicine practices within an academic medical centre. PARTICIPANTS: Patients aged 70 years and older with aspirin listed on the current medication list. METHODS: This is an electronic medical record-based chart review and educational intervention based on shared decision-making to reduce inappropriate aspirin use in primary practice. A chart review process was developed to identify the clinical indication for aspirin use. Patients taking aspirin for primary prevention were flagged for the primary care providers to review. Multilevel logistic regression models assessed factors affecting aspirin de-prescribing and longitudinal trend. RESULTS: Of 361 patients aged 70 years or older, 145 (40%) were taking aspirin for primary prevention of atherosclerotic cardiovascular disease. After 9 months, aspirin was deprescribed in 42 (29%) of these patients. Patients seen by their providers during the study period had lower odds of having aspirin on their medication list (OR=0.87, 95% CI: 0.81, 0.94) as compared with patients taking aspirin who were not seen by their healthcare provider. CONCLUSION: This is the first study to develop and implement a method of identifying potentially inappropriate aspirin use based on recent clinical evidence highlighting the risk of aspirin use for primary prevention in older adults. Future initiatives can leverage existing electronic medical record platforms to efficiently identify patients and expand these efforts to larger patient populations.

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Cite This Study

Brooker et al. (2023) conducted an observational in Inappropriate aspirin use for primary prevention (n=361). EMR-based chart review and educational intervention vs. Patients not seen by their healthcare provider was evaluated on Having aspirin on medication list (OR 0.87, 95% CI 0.81-0.94). An EMR-based educational intervention led to aspirin deprescribing in 29% of older adults, with patients seen by providers having lower odds of continued use (OR 0.87; 95% CI 0.81-0.94).

synapsesocial.com/papers/6a0fcb278090e499da602ea8https://doi.org/10.1136/bmjoq-2023-002457
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