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March 10, 2009Journal of General Internal Medicine135 citationsOpen Access

Obesity and Mammography: A Systematic Review and Meta-Analysis

NMNisa M. MaruthurSBShari BolenFBFrederick L. Brancati

Key Points

  • This review aims to quantify the relationship between body weight and mammography utilization among white and black women.
  • Systematic review of original articles evaluating body weight and mammography in the U.S.
  • Inclusion of 17 studies, focusing on self-reported BMI and excluding women under 40 years old.
  • Data analyzed using random-effects models with odds ratios calculated for different BMI categories.
  • Odds ratios for mammography in obese women compared to normal-weight women were 0.79 to 1.01, indicating lower screening rates.
  • Inverse association in mammography rates was observed in white but not black women.
  • Findings suggest lower screening rates may contribute to higher breast cancer mortality in morbidly obese women.

Abstract

BACKGROUND: Obese women experience higher postmenopausal breast cancer risk, morbidity, and mortality and may be less likely to undergo mammography. OBJECTIVES: To quantify the relationship between body weight and mammography in white and black women. DATA SOURCES AND REVIEW METHODS: We identified original articles evaluating the relationship between weight and mammography in the United States through electronic and manual searching using terms for breast cancer screening, breast cancer, and body weight. We excluded studies in special populations (e.g., HIV-positive patients) or not written in English. Citations and abstracts were reviewed independently. We abstracted data sequentially and quality information independently. RESULTS: Of 5,047 citations, we included 17 studies in our systematic review. Sixteen studies used self-reported body mass index (BMI) and excluded women or =40 kg/m(2)) obese women, respectively, compared to normal-weight women. Results were consistent when all available studies were included. The inverse association was found in white, but not black, women in the three studies with results stratified by race. CONCLUSIONS: Morbidly obese women are significantly less likely to report recent mammography. This relationship appears stronger in white women. Lower screening rates may partly explain the higher breast cancer mortality in morbidly obese women.

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Cite This Study

Maruthur et al. (2009) studied this question.

synapsesocial.com/papers/6a0fd7175725bbd5cc60248ahttps://doi.org/10.1007/s11606-009-0939-3
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