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October 1, 1995Journal of the American Chemical Society489 citations

Naked Protein Conformations: Cytochrome c in the Gas Phase

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DCDavid E. ClemmerRHRobert R. HudginsMJMartin F. Jarrold

Key Points

  • Investigate the structural conformations and folding stability of desolvated cytochrome c ions in the gas phase.
  • Analyzed gas-phase cytochrome c ions using electrospray ionization coupled with ion mobility spectrometry.
  • Measured cross-sectional collision areas to resolve different conformational charge states without solvent molecules.
  • Gas-phase cytochrome c adopts multiple discrete conformational states that depend strongly on total charge state.
  • Lower charge states retain compact, folded-like geometries despite the complete absence of surrounding solvent molecules.

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNaked Protein Conformations: Cytochrome c in the Gas PhaseDavid E. Clemmer, Robert R. Hudgins, and Martin F. JarroldCite this: J. Am. Chem. Soc. 1995, 117, 40, 10141–10142Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/ja00145a037https://doi.org/10.1021/ja00145a037research-articleACS PublicationsRequest reuse permissionsArticle Views1494Altmetric-Citations437LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

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Cite This Study

Clemmer et al. (1995) studied this question.

synapsesocial.com/papers/6a0ffdc42badbc352aff1a30https://doi.org/10.1021/ja00145a037
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