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March 24, 1988New England Journal of Medicine495 citations

The Appropriateness of Carotid Endarterectomy

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CWConstance M. WinslowDSDiane H. SolomonMCM R Chassin

Key Result

Carotid endarterectomy was substantially overused, with only 35% of procedures performed for appropriate reasons and 32% for inappropriate reasons, alongside a 9.8% major complication rate.

Study Design

Type

Observational (n=1,302)

Multicenter

Yes

Structured PICO

Is carotid endarterectomy performed for appropriate indications and what is the associated complication rate in Medicare patients?

P
Population
1,302 Medicare patients in three geographic areas who underwent carotid endarterectomy in 1981
I
Intervention
Carotid endarterectomy
O
Outcome
Appropriateness of the procedure (categorized as appropriate, equivocal, or inappropriate based on an expert panel rating)safety

Carotid endarterectomy was substantially overused in the studied Medicare population, with nearly a third of procedures deemed inappropriate and a high major complication rate of 9.8%.

Abstract

Carotid endarterectomy is a commonly performed but controversial procedure. We developed from the literature a list of 864 possible reasons for performing carotid endarterectomy, and asked a panel of nationally known experts to rate the appropriateness of each indication using a modified Delphi technique. On the basis of the panel's ratings, we determined the appropriateness of carotid endarterectomy in a random sample of 1302 Medicare patients in three geographic areas who had had the procedure in 1981. Thirty-five percent of the patients in our sample had carotid endarterectomy for appropriate reasons, 32 percent for equivocal reasons, and 32 percent for inappropriate reasons. Of the patients having inappropriate surgery, 48 percent had less than 50 percent stenosis of the carotid artery that was operated on. Fifty-four percent of all the procedures were performed in patients without transient ischemic attacks in the carotid distribution. Of these procedures, 18 percent were judged appropriate, as compared with 55 percent judged appropriate in patients with transient ischemic attacks in the carotid distribution. After carotid endarterectomy, 9.8 percent of patients had a major complication (stroke with residual deficit at the time of hospital discharge or death within 30 days of surgery). We conclude that carotid endarterectomy was substantially overused in the three geographic areas we studied. Furthermore, in situations in which the complication rate is equal to or above the study's aggregate rate, carotid endarterectomy would not be warranted, even in cases with an appropriate indication, because the risks would almost certainly outweigh the benefits.

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Cite This Study

Winslow et al. (1988) conducted an observational in Carotid endarterectomy (n=1,302). Carotid endarterectomy was evaluated on Appropriateness of carotid endarterectomy. Carotid endarterectomy was substantially overused, with only 35% of procedures performed for appropriate reasons and 32% for inappropriate reasons, alongside a 9.8% major complication rate.

synapsesocial.com/papers/6a100a378090e499da6086d3https://doi.org/10.1056/nejm198803243181201
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