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September 11, 2014European Heart Journal Acute Cardiovascular Care29 citations

Comparative care and outcomes for acute coronary syndromes in Central and Eastern European Transitional countries: A review of the literature

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FSFraser GD SmithRBRichard BroganOAOras Alabas

Key Result

A review of ACS care in Central and Eastern European Transitional countries revealed substantial geographical variation, with in-hospital AMI mortality ranging from 6.3% to 15.3%.

Structured PICO

How do quality of care and outcomes for acute coronary syndromes vary across Central and Eastern European Transitional countries?

P
Population
17 manuscripts covering patients with acute coronary syndrome (ACS), including acute myocardial infarction (AMI) and ST-elevation myocardial infarction (STEMI), in 19 Central and Eastern European Transitional (CEET) countries.
I
Intervention
Acute cardiac care and emergency reperfusion strategies (primary percutaneous coronary intervention, fibrinolytic therapy)
C
Comparator
Geographical variation across CEET countries
O
Outcome
In-hospital mortality and rates of reperfusion therapyhard clinical

There is substantial geographical variation in early mortality and emergency reperfusion strategies for STEMI across Central and Eastern European Transitional countries, highlighting the need for improved acute cardiac care and data collection.

Limitations

  • Many CEET countries do not have published ACS care and outcomes data.
  • No published ACS management or outcome data for four of the 19 CEET countries studied

Abstract

AIMS: The purpose of this review was to compare quality of care and outcomes following acute coronary syndrome (ACS) in Central and Eastern European Transitional (CEET) countries. METHODS: This was a review of original ACS articles in CEET countries from PubMed, ISI Web of Science, Medline and Embase databases published in English from November 2003 to February 2014. RESULTS: Seventeen manuscripts fulfilled the search criteria. Of 19 CEET countries studied, there were no published ACS management or outcome data for four countries. In-hospital mortality for patients with acute myocardial infarction (AMI) ranged from 6.3% in the Czech Republic to 15.3% in Latvia. In-hospital mortality for ST-elevation myocardial infarction (STEMI) ranged from 3.0% in Poland to 20.7% in Romania. For STEMI, primary percutaneous coronary intervention (PCI) ranged from 1.0% to over 92.0%, fibrinolytic therapy from 0.0% to 49.6%, and no reperfusion therapy from 7.0% to 63.0%. CONCLUSION: Many CEET countries do not have published ACS care and outcomes data. Of those that do, there is evidence for substantial geographical variation in early mortality. Wide variation in emergency reperfusion strategies for STEMI suggests that acute cardiac care is likely to be modifiable and if addressed could reduce mortality from ACS in CEET countries. The collection of ACS care and outcomes data across Europe must be prioritised.

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Cite This Study

Smith et al. (2014) conducted a review in Acute coronary syndrome. A review of ACS care in Central and Eastern European Transitional countries revealed substantial geographical variation, with in-hospital AMI mortality ranging from 6.3% to 15.3%.

synapsesocial.com/papers/6a10c4fbd06b5b96589f7afchttps://doi.org/10.1177/2048872614551545
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