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September 1, 1971Circulation291 citationsOpen Access

Mean Velocity of Fiber Shortening

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Why the study?

Does the mean velocity of circumferential fiber shortening (mean V CF) accurately estimate LV contractility compared to instantaneous tension-velocity relations in patients with and without LV disease?

Population

50 patients, including 13 without left ventricular disease, 22 with LV myocardial disease, and 15 with…

Comparison

Measurement of mean velocity of circumferential… vs Instantaneous tension-velocity relations.

Design

Cross-sectional

Authors

JKJoel S. KarlinerJGJames H. GaultDEDwain L. Eckberg

Discussion

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Overview

May simplify LV contractility estimation from cineangiograms; leaves open prospective outcome validation.

Structured PICO

Does the mean velocity of circumferential fiber shortening (mean V CF) accurately estimate LV contractility compared to instantaneous tension-velocity relations in patients with and without LV disease?

P
Population
50 patients, including 13 without left ventricular (LV) disease, 22 with LV myocardial disease, and 15 with valvular lesions and abnormal V CF at max T.
I
Intervention
Measurement of mean velocity of circumferential fiber shortening (mean V CF) determined from the systolic excursion of the LV internal minor equator obtained by cineangiography.
C
Comparator
Instantaneous tension-velocity relations (V CF at max T).
O
Outcome
Detection of impaired myocardial function and comparison of mean V CF with instantaneous tension-velocity relations.surrogate

Mean velocity of circumferential fiber shortening (mean V CF) provides a simplified, accurate method for estimating left ventricular contractility using only two frames of a cineangiogram.

Cite This Study

Karliner et al. (1971) studied this question.

synapsesocial.com/papers/6a11d076dcb035f2f8fd3ba5https://doi.org/10.1161/01.cir.44.3.323
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