Therapeutic plasma exchange (PLEX) was utilized in a single case of cardiogenic shock secondary to amiodarone-induced thyrotoxicosis, emphasizing the need for individualized treatment decisions.
Case Report (n=1)
Therapeutic plasma exchange is a potential individualized treatment option for severe amiodarone-induced thyrotoxicosis presenting with cardiogenic shock.
Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as "PLEX" may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.
Ahuja et al. (2023) conducted a case report in Amiodarone-induced thyrotoxicosis with cardiogenic shock (n=1). Therapeutic plasma exchange (PLEX) was evaluated. Therapeutic plasma exchange (PLEX) was utilized in a single case of cardiogenic shock secondary to amiodarone-induced thyrotoxicosis, emphasizing the need for individualized treatment decisions.