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September 8, 2020JAMA Internal Medicine64 citationsOpen Access

Representation of Older Adults in Cardiovascular Disease Trials Since the Inclusion Across the Lifespan Policy

MNMichael G. NannaSCSean T. ChenANAdam J. Nelson

Key Result

The NIH Inclusion Across the Lifespan Policy was evaluated to determine its impact on the representation of older adults in US interventional cardiovascular disease trials.

Structured PICO

Does the National Institutes of Health’s Inclusion Across the Lifespan Policy improve the representation of older adults in interventional cardiovascular disease studies in the US?

P
Population
interventional cardiovascular disease studies in the US
I
Intervention
implementation of the National Institutes of Health’s Inclusion Across the Lifespan Policy
C
Comparator
before implementation of the policy
O
Outcome
representation of older adults

This review evaluates whether the NIH Inclusion Across the Lifespan Policy successfully improved the representation of older adults in US cardiovascular trials.

Abstract

This review compares representation of older adults in interventional cardiovascular disease studies in the US before and after implementation of the National Institutes of Health’s Inclusion Across the Lifespan Policy.

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Cite This Study

Nanna et al. (2020) studied this question. The NIH Inclusion Across the Lifespan Policy was evaluated to determine its impact on the representation of older adults in US interventional cardiovascular disease trials.

synapsesocial.com/papers/6a1236fac031bb6829a61cb2https://doi.org/10.1001/jamainternmed.2020.2750
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Underrepresentation of Women, Elderly Patients, and Racial Minorities in the Randomized Trials Used for Cardiovascular Guidelines2014 · 170 citations
  2. 2Inclusion Across the Lifespan2018 · 115 citations
  3. 3The Gap Between Clinical Trials and the Real World2014 · 39 citations
  4. 4Examining the Evidence: A Systematic Review of the Inclusion and Analysis of Older Adults in Randomized Controlled Trials2011 · 399 citations
  5. 5Eligibility Criteria of Randomized Controlled Trials Published in High-Impact General Medical Journals2007 · 1,070 citations