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May 24, 2026Guangming Journal of Chinese Medicine0 citations

Study on the Effects of Qigui Antipruritic Granules on Clinical Symptoms and Skin Barrier Function in Senile Pruritus

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MWMingming WUYZYiou ZHANGYWYuan Wang

Key Points

  • This study aims to evaluate the effects of Qigui Antipruritic Granules on clinical symptoms and skin barrier function in elderly patients with pruritus.
  • A total of 100 elderly patients with pruritus were randomly assigned to either experimental or control groups, with 50 in each group.
  • The experimental group received Qigui Antipruritic Granules, while the control group received a moisturizing capsule for 4 weeks.
  • The study assessed pruritus severity and skin barrier function before and after treatment.
  • The experimental group showed lower pruritus symptom scores than the control group (P<0.05).
  • Skin dryness scores decreased significantly in the experimental group (P<0.05).
  • There was a significant increase in stratum corneum hydration in the experimental group (P<0.05), and transdermal water loss reduced (P<0.05).

Abstract

摘要: 目的 研究芪归止痒颗粒对血虚风燥型老年皮肤瘙痒症患者临床症状及皮肤屏障功能的作用,为老年皮肤瘙痒症的临床治疗提供安全有效的方案。 方法 选取2024年1月—2024年12月山西省中医院皮肤科门诊老年皮肤瘙痒症患者100例,随机分为试验组和对照组,每组50例。试验组口服芪归止痒颗粒,对照组口服润燥止痒胶囊,疗程均为4周。观察2组患者治疗前后的瘙痒症状评分(包括瘙痒程度、瘙痒部位、瘙痒频率)及皮肤屏障功能指标(皮肤干燥程度、角质层含水量、经皮水分丢失量)。 结果 治疗后,试验组瘙痒症状评分低于对照组(pppp 结论 芪归止痒颗粒能够显著改善血虚风燥型老年皮肤瘙痒症患者的临床症状及皮肤屏障功能,且安全性良好。

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Cite This Study

WU et al. (2026) studied this question.

synapsesocial.com/papers/6a12955d48a0ea166567174bhttps://doi.org/10.70976/j.issn.1003-8914.2026.04.012
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