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May 1, 2004European Journal of Heart Failure44 citations

The ‘real’ Woman with Heart Failure. Impact of Sex on Current In-Hospital Management of Heart Failure by Cardiologists and Internists

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COCristina OpasichSFS. De FeoGAGiuseppe Ambrosio

Key Result

Women admitted with heart failure received fewer diagnostic procedures and evidence-based medications than men, despite having similar in-hospital mortality and 6-month event rates.

Key Points

  • To evaluate sex-based differences in clinical characteristics, diagnostic and therapeutic resource utilization, management, and outcomes among patients hospitalized with heart failure.
  • Conducted a prospective cross-sectional survey of 2,127 consecutive patients (47% women) admitted for heart failure across 167 cardiology and 250 internal medicine departments between February 14 and 25, 2000.
  • Assessed in-hospital management strategies, invasive and non-invasive procedure rates, pharmacotherapy, in-hospital mortality, and 6-month follow-up outcomes.
  • Women were older, presented more frequently with atrial fibrillation and hypertensive or valvular etiologies, and were more often admitted to internal medicine rather than cardiology units.
  • Female patients underwent fewer invasive and non-invasive procedures and were prescribed ACE-inhibitors, amiodarone, and spironolactone less frequently, but received digoxin more frequently than men.
  • In-hospital mortality was similar across sexes and healthcare provider settings, while nearly half of all patients were readmitted at least once during 6-month follow-up.

Study Design

Type

Cross-Sectional (n=2,127)

Multicenter

Yes

Structured PICO

Are there sex differences in the clinical profile, management, and outcomes of patients hospitalized with heart failure?

P
Population
2127 consecutive patients (47% women) admitted with heart failure to 167 cardiology and 250 internal medicine departments
O
Outcome
Differences between sexes in the clinical profile, use of resources, management and outcome (including in-hospital mortality and 6-month events)

Women hospitalized with heart failure receive fewer diagnostic procedures and evidence-based pharmacological therapies compared to men, highlighting a potential sex disparity in heart failure management.

Abstract

AIM: To identify differences between sexes in the clinical profile, use of resources, management and outcome in a large population of 'real world' patients with heart failure (HF). METHODS: A prospective cross-sectional survey was conducted on 2127 consecutive patients (47% women) admitted with HF to 167 cardiology and 250 internal medicine departments between February 14 and 25, 2000. RESULTS: Women were older, had a higher prevalence of atrial fibrillation, and more frequently a hypertensive or valvular aetiology. Females were admitted more frequently in Medical than in Cardiology Departments. The rate of invasive and non-invasive procedures was lower in women than in men, slightly higher if managed by cardiologists. Women were less frequently prescribed ACE-inhibitors, amiodarone, and spironolactone, and more frequently prescribed digoxin. In-hospital mortality was similar, without difference between health-care providers. A 6-month follow-up was performed in 56.4% of the cases in both setting, but less frequently in women. Event rates were similar with nearly half of patients re-hospitalised at least once. CONCLUSION: The 'real' HF woman has generally a more severe disease; she is an old lady who is more frequently hospitalised in a medical unit, receives few diagnostic, and cardiovascular procedures and pharmacological therapy, has a relatively low probability of dying in hospital, but a high likelihood of requiring readmission.

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Cite This Study

Opasich et al. (2004) conducted a cross-sectional in Heart failure (n=2,127). Female sex vs. Male sex was evaluated on In-hospital mortality and 6-month event rates. Women admitted with heart failure received fewer diagnostic procedures and evidence-based medications than men, despite having similar in-hospital mortality and 6-month event rates.

synapsesocial.com/papers/6a12cdeb257f24f1de9e519ehttps://doi.org/10.1016/j.ejheart.2003.11.021
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