Idiopathic scrotal calcinosis (ISC) is a rare benign condition characterized by the gradual development of multiple painless calcified nodules confined to the scrotal skin. Although its exact origin remains poorly understood, several pathogenic mechanisms have been proposed, and its etiology continues to be debated. We report two cases of ISC in young adult males presenting with slowly progressive scrotal nodules, highlighting the characteristic clinical features of this uncommon entity, the role of surgical excision as definitive treatment, and the importance of histopathological examination in establishing the diagnosis.
Laknizi et al. (2026) studied this question.