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May 25, 2026BMC Cardiovascular Disorders0 citationsOpen Access

BiatriaL cardiac extension of Burkitt lymphoma: a case report of successful surgical correction

YKYurii KharenkoIMIhor MokrykVDVitaly Demyanchuk

Key Result

Emergency surgical debulking using endotracheal tube-assisted inferior vena cava cannulation successfully restored hemodynamics and bridged a patient with biatrial Burkitt lymphoma to chemotherapy.

Key Points

  • To present a unique surgical case of biatrial cardiac involvement by Burkitt lymphoma and the effectiveness of an unconventional venous cannulation technique.
  • Emergency surgery performed on a 30-year-old male with acute heart failure and significant hemodynamic instability.
  • Unconventional technique using a cuffed endotracheal tube for inferior vena cava cannulation during cardiopulmonary bypass.
  • Histopathological and molecular analysis to confirm diagnosis and determine treatment plan.
  • Effective tumor debulking restored intracardiac blood flow.
  • Patient achieved complete metabolic remission at one-year follow-up on ¹⁸F-FDG PET/CT (Deauville score 1).
  • Molecular analysis confirmed Burkitt lymphoma with high proliferative index and c-MYC gene translocation.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
1 30-year-old male presenting with acute heart failure and severe hemodynamic instability caused by massive biatrial involvement of Burkitt lymphoma
I
Intervention
Emergency surgery with tumor debulking using a cuffed endotracheal tube as a temporary inferior vena cava cannula, followed by systemic chemotherapy
O
Outcome
Complete metabolic remission on ¹⁸F-FDG PET/CT

Emergency surgical debulking using an endotracheal tube for IVC cannulation can serve as a successful bridge to chemotherapy in life-threatening cardiac Burkitt lymphoma.

Limitations

  • Preoperative PET/CT imaging was not feasible due to the emergency nature of the case, which limits direct comparison with follow-up imaging.

Abstract

Primary cardiac tumors are rare, and cardiac involvement by Burkitt lymphoma is exceptionally uncommon, particularly when presenting with extensive intracavitary growth. Such tumors may rapidly lead to hemodynamic compromise due to obstruction of venous inflow and impairment of cardiac filling, often requiring urgent surgical intervention. Establishing cardiopulmonary bypass in these settings may be technically challenging, especially when conventional inferior vena cava cannulation is precluded by tumor extension. We report a unique case of a 30-year-old male who presented with acute heart failure and severe hemodynamic instability caused by massive biatrial involvement of Burkitt lymphoma. Imaging revealed large intracavitary tumors extending into the inferior vena cava and pulmonary veins, resulting in near-complete obstruction of venous return. During emergency surgery, standard inferior vena cava cannulation and snaring were not feasible due to tumor invasion. To achieve adequate venous drainage and enable cardiopulmonary bypass, an unconventional technique using a cuffed endotracheal tube as a temporary inferior vena cava cannula was successfully employed. This approach allowed effective tumor debulking, restoration of intracardiac blood flow, and subsequent initiation of definitive systemic chemotherapy. Histopathological and molecular analysis confirmed Burkitt lymphoma with a high proliferative index and c-MYC gene translocation. At one-year follow-up, the patient demonstrated complete metabolic remission on ¹⁸F-FDG PET/CT (Deauville score 1). This case illustrates the critical role of emergency surgical intervention as a bridge to definitive chemotherapy in life-threatening cardiac lymphoma. Our experience extends the applicability of endotracheal tube–assisted venous cannulation beyond its original description and suggests that this technique may serve as a valuable bailout option in emergency cardiac oncology surgery when conventional inferior vena cava cannulation is technically impossible.

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Cite This Study

Kharenko et al. (2026) conducted a case report in Biatrial cardiac extension of Burkitt lymphoma (n=1). Emergency surgical debulking with endotracheal tube-assisted inferior vena cava cannulation and systemic chemotherapy was evaluated on Survival and metabolic remission. Emergency surgical debulking using endotracheal tube-assisted inferior vena cava cannulation successfully restored hemodynamics and bridged a patient with biatrial Burkitt lymphoma to chemotherapy.

synapsesocial.com/papers/6a13e8520e02ee3982d3302ahttps://doi.org/10.1186/s12872-026-06023-0
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