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International multicenter randomized-controlled trial comparing morbidity and quality of life between laparoscopy-assisted and totally laparoscopic distal gastrectomy for gastric cancer

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Randomized trial compares postoperative outcomes in gastric cancer patients, indicating differences in complications and quality of life.

This trial aims to compare postoperative morbidity and quality of life between laparoscopy-assisted and totally laparoscopic distal gastrectomy for gastric cancer.
International randomized controlled trial including 884 patients with gastric adenocarcinoma.
Patients were assigned to laparoscopy-assisted or totally laparoscopic procedures from 2018 to 2021.
Quality of life was assessed using EORTC questionnaires at multiple time points after surgery.
Early complication rates were 8.9% in the TLDG group and 11.1% in the LADG group (P = .33).
Postoperative ileus rates were 0.7% in TLDG and 3.6% in LADG (P = .007).
QoL scores showed transient improvements in constipation, fatigue, and anxiety for TLDG but no overall difference at 12 months.

Min et al. (2026) studied this question.

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View Full Paper

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Authors

Randomized trial compares postoperative outcomes in gastric cancer patients, indicating differences in complications and quality of life.

This trial aims to compare postoperative morbidity and quality of life between laparoscopy-assisted and totally laparoscopic distal gastrectomy for gastric cancer.
International randomized controlled trial including 884 patients with gastric adenocarcinoma.
Patients were assigned to laparoscopy-assisted or totally laparoscopic procedures from 2018 to 2021.
Quality of life was assessed using EORTC questionnaires at multiple time points after surgery.
Early complication rates were 8.9% in the TLDG group and 11.1% in the LADG group (P = .33).
Postoperative ileus rates were 0.7% in TLDG and 3.6% in LADG (P = .007).
QoL scores showed transient improvements in constipation, fatigue, and anxiety for TLDG but no overall difference at 12 months.

Min et al. (2026) studied this question.

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