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July 12, 1988Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE25 citations

Near-Field Scanning Optical Microscopy (NSOM)

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EBEric BetzigMIM. IsaacsonHBH. Barshatzky

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Abstract

Superresolution optical images have been generated with near-field scanning optical microscopy (NSOM). The underlying concept is presented and several modes of operation are discussed. A resolution based on edge sharpness of 70 nm or better has been demonstrated with two different instruments. Images have been obtained which characterize the resolution as a function of two critical parameters: the aperture size and the aperture-sample separation. The near-field images also illustrate novel features resulting from several forms of contrast. Finally, the potential of NSOM is compared with conventional lens-based forms of microscopy as well as with more recent scanned tip methods.

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Betzig et al. (1988) studied this question.

synapsesocial.com/papers/6a14bf37a8829aa21862cfddhttps://doi.org/10.1117/12.944521
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