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April 24, 2015Frontiers in Endocrinology144 citationsOpen Access

Adipose Tissue Dysfunction and Impaired Metabolic Health in Human Obesity: A Matter of Oxygen?

GGGijs H. GoossensEBEllen E. Blaak

Key Result

Alterations in adipose tissue oxygen tension may drive adipose tissue dysfunction in human obesity, though further research is needed to clarify the functional consequences of these changes.

PICO

P
Population
Obesity

Limitations

  • In vitro studies often use extremely low or high oxygen levels that do not reflect physiological conditions.
  • Conflicting results exist regarding whether human adipose tissue is hypoxic or hyperoxic in obesity.

Abstract

OPINION article Front. Endocrinol., 24 April 2015Sec. Systems Endocrinology https://doi.org/10.3389/fendo.2015.00055

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Cite This Study

Goossens et al. (2015) conducted an editorial in Obesity. Alterations in adipose tissue oxygen tension may drive adipose tissue dysfunction in human obesity, though further research is needed to clarify the functional consequences of these changes.

synapsesocial.com/papers/6a14e394253bd9cd3ce62746https://doi.org/10.3389/fendo.2015.00055
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