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August 2, 2017Journal of the American Heart Association31 citationsOpen Access

Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms

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Why the study?

Does omnipolar electrogram assessment improve the consistency of ventricular myocardial voltage mapping compared to bipolar electrograms in isolated hearts?

Population

15 isolated hearts (5 healthy rabbits, 5 healthy pigs, and 5 diseased humans)

Comparison

Omnipolar electrogram methodology for voltage… vs Bipolar electrograms and Vpps along horizontal…

Design

Preclinical

Key result

Omnipolar electrograms provided physiologically relevant voltages that were highly correlated with maximal bipolar electrograms (0.97±0.08) and demonstrated greater beat-by-beat consistency.

Authors

KMKarl MagtibaySMStéphane MasséJAJohn Asta

Discussion

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Overview

Omnipolar mapping may enhance voltage consistency in ventricular substrate assessment; hypothesis-generating in animal models and requires human validation before practice change.

Structured PICO

Does omnipolar electrogram assessment improve the consistency of ventricular myocardial voltage mapping compared to bipolar electrograms in isolated hearts?

P
Population
15 isolated hearts (5 healthy rabbits, 5 healthy pigs, and 5 diseased humans)
I
Intervention
Omnipolar electrogram methodology for voltage peak-to-peak (Vpps) assessment
C
Comparator
Bipolar electrograms and Vpps along horizontal and vertical orientations
O
Outcome
Voltage map consistency and correlation between omnipolar and bipolar electrograms under paced conditionssurrogate

Omnipolar electrograms provide more consistent and orientation-independent voltage assessments compared to traditional bipolar electrograms in ventricular myocardial mapping.

Cite This Study

Magtibay et al. (2017) studied Ventricular tachycardia (n=15). Omnipolar electrograms vs. Bipolar electrograms was evaluated on Voltage peak-to-peak (Vpps) and correlation between omnipolar and bipolar electrograms. Omnipolar electrograms provided physiologically relevant voltages that were highly correlated with maximal bipolar electrograms (0.97±0.08) and demonstrated greater beat-by-beat consistency.

synapsesocial.com/papers/6a153befcb0379474a82099dhttps://doi.org/10.1161/jaha.117.006447
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