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June 1, 1985Annual Review of Biochemistry397 citations

Cell Adhesion and the Molecular Processes of Morphogenesis

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GEGerald M. Edelman

Key Points

  • To explore the role of the Hippo pathway in regulating cell adhesion and morphogenesis during tissue development.
  • Investigated the Hippo signaling pathway in Drosophila melanogaster as a model organism.
  • Analyzed its effects on various biological processes including cell growth and organ size.
  • The Hippo pathway significantly influences tissue growth regulation.
  • Dysregulation of the Hippo pathway was linked to abnormalities in cell adhesion and morphogenetic processes.

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

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Cite This Study

Gerald M. Edelman (1985) studied this question.

synapsesocial.com/papers/6a15c2f7cb0379474a827faahttps://doi.org/10.1146/annurev.bi.54.070185.001031
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