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May 27, 2026BMC Anesthesiology0 citationsOpen Access

Current status of neuromuscular reversal and neuromuscular monitoring in China: a cross-sectional survey

JTJia-chun TaoSecond Affiliated Hospital of Zhejiang UniversityXZXiang-yong ZhouSecond Affiliated Hospital of Zhejiang UniversityTWT Q WangFirst Hospital of China Medical University

Key Result

Routine administration of pharmacological reversal agents was reported by 40.09% of Chinese anesthesia providers, while only 1.61% routinely utilized quantitative neuromuscular monitoring.

Key Points

  • The aim is to assess the practices of neuromuscular reversal and monitoring among anesthesiologists in China and identify gaps in adherence to best practices.
  • Conducted a cross-sectional survey with a 25-question questionnaire among anesthesiologists in China.
  • Analyzed 3,168 valid responses collected over 30 days via online platforms.
  • Used descriptive statistics, chi-square tests, and logistic regression analysis to interpret the data.
  • Only 40.09% routinely used reversal agents, predominantly neostigmine (61.11%).
  • Quantitative neuromuscular monitoring was utilized by only 1.61%, with 98.01% relying on subjective assessments.
  • Advanced education and higher academic rank were linked to better adherence to monitoring practices.

Study Design

Type

Cross-Sectional (n=3,168)

Multicenter

Yes

Structured PICO

What are the current practices of neuromuscular reversal and neuromuscular monitoring among anesthesiologists in China?

P
Population
3,168 anesthesiologists in China
I
Intervention
Survey on current practices of neuromuscular reversal and neuromuscular monitoring
O
Outcome
Current practices and adoption rates of neuromuscular reversal and monitoring

There are substantial gaps in adherence to evidence-based practices for managing residual neuromuscular blockade in China, with significant underutilization of quantitative monitoring and reversal agents.

Abstract

Residual neuromuscular blockade (rNMB) is associated with perioperative pulmonary complications. Effective neuromuscular monitoring and the use of reversal agents can help reduce rNMB. We surveyed the current practices of neuromuscular reversal and neuromuscular monitoring among anesthesiologists in China. We released a questionnaire containing 25 questions via the New Youth Anesthesia Forum and promoted it through WeChat. We allowed one submission from each IP address. The survey was available online for 30 days. Data were analyzed using descriptive statistics, chi-square tests, and logistic regression analysis. We analyzed 3,168 valid questionnaires. Rocuronium (41.76%) and cisatracurium (38.83%) were the most frequently used neuromuscular blocking agents. Only 40.09% of respondents routinely administered pharmacological reversal agents, with neostigmine being the predominant choice (61.11% of total respondents) and sugammadex used by merely 19.03%. The adoption of quantitative neuromuscular monitoring was low, with only 1.61% (n = 51) reported routinely utilizing quantitative monitoring (TOF ratio measurement), while 98.01% relied solely on subjective clinical signs. Logistic regression identified that advanced education (master’s or higher) and senior academic rank (associate chief or chief physician) independently predicted greater adoption of neuromuscular monitoring. Anesthesiologists in primary and secondary hospitals demonstrated significantly lower adherence to both antagonist administration and objective monitoring compared to those in tertiary centers. Our findings reveal substantial gaps in adherence to evidence-based practices for managing rNMB in China, particularly concerning the underutilization of quantitative monitoring and sugammadex. Systemic interventions to improve equipment accessibility, drug availability, and targeted education are crucial to enhance patient safety. Policy-driven resource allocation and standardized training programs are recommended to bridge the gap between evidence and practice.

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Cite This Study

Tao et al. (2026) conducted a cross-sectional in Neuromuscular reversal and monitoring practices (n=3,168). Neuromuscular monitoring and reversal agents was evaluated on Routine administration of pharmacological reversal agents. Routine administration of pharmacological reversal agents was reported by 40.09% of Chinese anesthesia providers, while only 1.61% routinely utilized quantitative neuromuscular monitoring.

synapsesocial.com/papers/6a168b160c924ddd1bd59e04https://doi.org/10.1186/s12871-026-03913-w
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