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January 28, 2006Journal of the American Chemical Society142 citationsOpen Access

Dendritic Folate Rosettes as Ion Channels in Lipid Bilayers

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NSNaomi SakaiYKYuko KamikawaMNMasayuki Nishii

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Abstract

The self-assembly of folate dendrimers into pi-stacked supramolecular rosettes is shown to produce ion channels in planar and spherical lipid bilayer membranes. The found ion channels are small, quite homogeneous, long-lived, ohmic, cation selective (Eisenman I), and blockable by the permeant cation.

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Sakai et al. (2006) studied this question.

synapsesocial.com/papers/6a16aa3d77556771e2b26e6bhttps://doi.org/10.1021/ja058157k
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