Effect of Radio Frequency Inhomogeneity Correction on the Reproducibility of Intra‐Cranial Volumes Using MR Image Data

The volumes of total brain, white matter, gray matter, and cerebrospinal fluid in normal volunteers were determined using a supervised nonparametric feature map segmentation of dual-contrast MR images after correcting for the radio frequency (RF) inhomogeneity. Reproducibility of the segmentation was evaluated in terms of inter-observer and scan-to-scan variations. A comparison with the published results indicates that the scan-to-scan and inter-observer variabilities in the determination of tissue volumes are substantially reduced following the RF inhomogeneity correction.