A System of Scoring Linkage Data, with Special Reference to the Pied Factors in Mice

(1) Gates' and Pullig's discovery of linkage between hairless (hr) and dominant spotting (W) shows that, contrary to previous statements, W and s also must be linked. (2) New data are given showing significant linkage, and a review of the data previously available shows it to be homogeneous and uniformly to favor linkage; previous compilations have therefore been misleading. (3) A method is given of scoring linkage data so that the evidence available from data of various kinds can easily be combined, and its heterogeneity examined. (4) The method is illustrated with the problem of fitting consistent map distances using Kosambi's formula.