• Biodegradable metallic stents are reviewed as translational vascular devices, with emphasis on Mg, Fe, Zn, and Mo systems and their distinct mechanical, degradation, biological, and clinical profiles. • Cardiovascular applications provide the major evidence base for biodegradable metals, including material optimization, device-level performance, preclinical validation, and clinical experience in coronary intervention. • Neurovascular translation requires dedicated re-engineering beyond coronary stent adaptation, due to intracranial vessel tortuosity, fragile arterial walls, perforator-rich anatomy, blood–brain barrier-related safety concerns, and stricter imaging requirements.
Xiao et al. (2026) studied this question.
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