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January 1, 2021IEEE Access55 citationsOpen Access

ResDUnet: A Deep Learning-Based Left Ventricle Segmentation Method for Echocardiography

AAAlyaa AmerXYXujiong YeFJFaraz Janan

Key Result

ResDUnet outperformed state-of-the-art methods for left ventricle segmentation, achieving a Dice similarity increase of 8.4% and 1.2% compared to deeplabv3 and U-net, respectively.

Structured PICO

Does ResDUnet improve left ventricle segmentation accuracy in echocardiographic images compared to existing deep learning models?

P
Population
2000 echocardiographic images acquired from 500 patients with large variability in quality and patient pathology
I
Intervention
ResDUnet (a deep learning segmentation method based on U-net incorporating cascaded dilated convolution and residual blocks with squeeze and excitation units)
C
Comparator
deeplabv3 and U-net
O
Outcome
Dice similarity for left ventricle segmentationsurrogate

ResDUnet, a novel deep learning model, improves automated left ventricle segmentation accuracy on echocardiography compared to standard U-net and deeplabv3 models.

Main Result

Effect estimate: Dice similarity increase 8.4% and 1.2%

Abstract

Segmentation of echocardiographic images is an essential step for assessing the cardiac functionality and providing indicative clinical measures, and all further heart analysis relies on the accuracy of this process. However, the fuzzy nature of echocardiographic images degraded by distortion and speckle noise poses some challenges on the manual segmentation task. In this paper, we propose a fully automated left ventricle segmentation method that can overcome those challenges. Our method performs accurate delineation for the ventricle boundaries despite the ill-defined borders and shape variability of the left ventricle. The well-known deep learning segmentation model, known as the U-net, has addressed some of these challenges with outstanding performance. However, it still ignores the contribution of all semantic information through the segmentation process. Here we propose a novel deep learning segmentation method based on U-net, named ResDUnet. It incorporates feature extraction at different scales through the integration of cascaded dilated convolution. To ease the training process, residual blocks are deployed instead of the basic U-net blocks. Each residual block is enriched with a squeeze and excitation unit for channel-wise attention and adaptive feature re-calibration. The performance of the method is evaluated on a dataset of 2000 images acquired from 500 patients with large variability in quality and patient pathology. ResDUnet outperforms state-of-the-art methods with a Dice similarity increase of 8.4% and 1.2% compared to deeplabv3 and U-net, respectively. Furthermore, to demonstrate the impact of each proposed sub-module, several experiments have been carried out with different designs and variations of the integrated sub-modules. We also describe and discuss all technical elements of a deep-learning model via a step-by-step explanation of parameters and methods, while using our left ventricle segmentation as a case study, to explain the application of AI to echocardiographic imaging.

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Cite This Study

Amer et al. (2021) studied Left ventricle segmentation in echocardiography (n=500). ResDUnet vs. deeplabv3 and U-net was evaluated on Dice similarity (Dice similarity increase 8.4% and 1.2%). ResDUnet outperformed state-of-the-art methods for left ventricle segmentation, achieving a Dice similarity increase of 8.4% and 1.2% compared to deeplabv3 and U-net, respectively.

synapsesocial.com/papers/6a17f3c04f2b3115b0133a06https://doi.org/10.1109/access.2021.3122256
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnosis of left ventricular hypertrophy using convolutional neural network2020 · 21 citations
  2. 2ResDUnet: Residual Dilated UNet for Left Ventricle Segmentation from Echocardiographic Images2020 · 25 citations
  3. 3Validation of a novel automated border-detection algorithm for rapid and accurate quantitation of left ventricular volumes based on three-dimensional echocardiography2009 · 130 citations
  4. 4Deep Learning for Segmentation Using an Open Large-Scale Dataset in 2D Echocardiography2019 · 740 citations
  5. 5Fast and Fully Automatic Left Ventricular Segmentation and Tracking in Echocardiography Using Shape-Based B-Spline Explicit Active Surfaces2017 · 79 citations