Construction, expression, and evaluation of the naturally acquired humoral immune response against RMC-1 of Plasmodium vivax, a multistage chimeric protein

Key Points

• This research aims to construct and evaluate the immune response against the RMC-1 chimeric protein of Plasmodium vivax.
• Construction of the chimeric protein RMC-1
• Expression of the protein in a suitable system
• Evaluation of the humoral immune response elicited by the protein.
• Characterization of the immune response indicates a successful humoral response against RMC-1.
• Potential implications for creating future malaria vaccines leveraging this protein.
• Evaluation methods demonstrated specific antibody production in response to the chimeric protein.