PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 29, 2026Journal of Thermal Biology0 citationsOpen Access

Mitochondrial coupling efficiency is the first bioenergetic function to decline at Critical Thermal maximum (CTmax) in the skeletal muscle of a fish, the spirlin (Alburnoides bipunctatus)

View Full Paper
JWJulia WatsonAMAnthony MaireLGLéopold Ghinter

Key Points

  • This research aims to investigate mitochondrial function in spirlin muscle at varying temperatures, focusing on efficiency at critical thermal maximum (CTmax).
  • Tested mitochondrial function at 20°C and CTmax (34°C) in spirlin muscle.
  • Measured oxygen fluxes related to oxidative phosphorylation (OXPHOS) and leak.
  • Analyzed the efficiency of ATP production during thermal stress.
  • At CTmax, oxygen fluxes increased (OXPHOS and LEAK), but coupling efficiency (ATP/O) decreased significantly.
  • Muscle mitochondrial dysfunction at high temperatures may hinder locomotion in spirlin.
  • Study highlights critical role of mitochondrial efficiency in thermal tolerance.

Abstract

• Mitochondrial function in spirlin muscle was tested at 20°C and CTmax at 34°C. • At CTmax, fluxes (OXPHOS and LEAK) were higher, but efficiency (ATP/O) was lower. • This study underlines the role of muscle mitochondria in thermal tolerance. • Muscle mitochondria dysfunction at high temperatures may impair fish locomotion.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Watson et al. (2026) studied this question.

synapsesocial.com/papers/6a192c0ffab5b468c441509bhttps://doi.org/10.1016/j.jtherbio.2026.104493
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ecology, threats, and conservation of the spirlin Alburnoides bipunctatus (Bloch, 1782)2026 · 1 citations
  2. 2The Effect of Environmental Factors on the Physiology of Fish1971 · 1,755 citations
  3. 3Measuring critical thermal maximum in aquatic ectotherms: a practical guide2025 · 4 citations
  4. 4Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease2017 · 149 citations
  5. 5A unifying model to estimate thermal tolerance limits in ectotherms across static, dynamic and fluctuating exposures to thermal stress2021 · 145 citations