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May 29, 2026Journal of Clinical Oncology

Association between low muscle mass assessed by bioelectrical impedance analysis and clinical outcomes in hospitalized cancer patients.

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Authors

DTDiogo ToledoGYGabriel Bernardes YacoubFRFernanda Ribeiro

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Overview

Observational study assesses low muscle mass implications in hospitalized cancer patients, suggesting a need for better risk assessment tools.

Key Points

  • Evaluate body composition via bioelectrical impedance analysis and its association with clinical outcomes in hospitalized cancer patients.
  • Included 104 adult cancer patients admitted to a tertiary public hospital from January to October 2025.
  • Assessed muscle mass using bioelectrical impedance analysis and compared nutritional and functional parameters.
  • Analyzed correlations between muscle mass indicators and clinical outcomes such as length of hospital stay and in-hospital mortality.
  • 29.8% of patients had low muscle mass at admission.
  • Patients with low muscle mass had significantly lower BMI (23.3 vs 27.6 kg/m², p=0.001) and appendicular muscle index (6.20 vs 7.61, p<0.001).
  • In-hospital mortality was 18.5% for patients with low muscle mass compared to 7.0% for those without, but this was not statistically significant (p=0.133).

Cite This Study

Toledo et al. (2026) studied this question.

synapsesocial.com/papers/6a192e79fab5b468c44179e4https://doi.org/10.1200/jco.2026.44.16_suppl.11034
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Muscle Mass and Malnutrition in Patients with Colorectal Cancer Using the Global Leadership Initiative on Malnutrition Criteria and Comparing Bioelectrical Impedance Analysis and Computed Tomography Measurements2024 · 15 citations
  2. 2Body Composition by Bioelectrical Impedance Analysis: Associations with Nutritional Status, Functional Limitations, and Chronic Diseases in Older Adults2026 · 2 citations
  3. 3Comparison of Bioelectrical Impedance Analysis With Dual‐Energy X‐Ray Absorptiometry in the Assessment of Sarcopenia in Individuals With Type 2 Diabetes: A Cross‐Sectional Study2026
  4. 4The Usefulness of Anthropometric Measurements and Indicators in Assessing Muscle Mass in Older Adults2025 · 5 citations
  5. 5D23-07 Abnormalities in Body Composition Not Captured by Body Mass Index Are Associated With Reduced Functional Capacity in Adults With Advanced Interstitial Lung Disease2026