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September 1, 2020Automatic Control and Computer Sciences5 citations

Drug Adverse Reaction Discovery Based on Attention Mechanism and Fusion of Emotional Information

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KKKeming KangSTShengwei TianLYLong Yu

Key Points

  • The research aims to enhance the identification and classification of adverse drug reactions using a neural network model that integrates attention mechanisms and emotional information.
  • Developed ACB model combining attention mechanism with Bi-LSTM for drug reaction analysis.
  • Utilized emotional information from user medication comments to improve feature representation and classification accuracy.
  • Evaluated model performance using a local drug dataset from Xinjiang.
  • ACB achieved a precision of 95.12%, recall of 98.48%, and an F-score of 96.77% on the test dataset.
  • The proposed model significantly enhanced the recognition and classification performance for adverse drug reactions compared to conventional methods.

Abstract

This paper proposes a research method of adverse drug reactions based on attention mechanism and fusion of emotional information, and constructs a neural network model, Attention based Convolutional neural networks and Bi-directional long short-Term Memory (ACB). In order to improve the recognition efficiency of adverse drug reactions and solve the problems of gradient explosion and disappearance, it introduced the attention mechanism and Bi-directional Long Short-Term Memory (BiLSTM) to enhance the reliability of the model, as well as mixed together the emotional information of the users’ medication comments. Compared with the superficial information only relied on users’ medication reviews, this is able to enhance features’ expression way and the accuracy of the adverse drug reaction’s classifications. This experiment dataset was based on the local drugs in Xinjiang. The best performance on a test dataset was with ACB obtaining a precision of 95.12% and a recall of 98.48%, and an F-score of 96.77%. The results showed that the ACB model can significantly improve the recognition and classification performance of adverse drug reactions.

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Cite This Study

Kang et al. (2020) studied this question.

synapsesocial.com/papers/6a19c94f3f3ec013f0df1002https://doi.org/10.3103/s0146411620050053
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