What are the perioperative risk factors for postoperative renal dysfunction in patients undergoing cardiopulmonary bypass for coronary artery surgery?
Low cardiac output syndrome, banked blood transfusions, and low hematocrit during cardiopulmonary bypass are significant risk factors for severe postoperative renal dysfunction.
We studied 316 patients undergoing cardiopulmonary bypass for coronary artery surgery in order to determine perioperative risk factors for postoperative renal dysfunction. A preliminary univariate analysis was performed by chi 2 analysis for categorical data and Mann-Whitney U-test for continuous variables to detect significant correlations between each risk factor and the occurrence of moderate or severe renal dysfunction. Subsequently, a multiple logistic regression was applied to the three risk factors identified as predictive for severe renal dysfunction. Low cardiac output syndrome and need for banked blood transfusions combined with a low haematocrit value during cardiopulmonary bypass increase the probability of severe renal dysfunction in the postoperative course.
Ranucci et al. (1994) studied this question.