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August 31, 2012Angewandte Chemie International Edition287 citations

Rhodium‐Catalyzed Direct CH Amination of Benzamides with Aryl Azides: A Synthetic Route to Diarylamines

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JRJaeyune RyuKSKwangmin ShinSPSae Hume Park

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Abstract

No muss, no fuss: A rhodium-catalyzed direct intermolecular C-H amination of benzamides and ketoximes using aryl azides as the amine source has been developed. The reaction exhibits a broad substrate scope with excellent functional-group tolerance, requires no external oxidants, releases N(2) as the only by-product, and produces diarylamines in high yields.

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Ryu et al. (2012) studied this question.

synapsesocial.com/papers/6a1b09294dc16c762f0c6b3fhttps://doi.org/10.1002/anie.201205723
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