PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
December 23, 2008Obesity Reviews383 citations

Obesity as an independent risk factor for elective and emergency caesarean delivery in nulliparous women – systematic review and meta‐analysis of cohort studies

View Full Paper
APAmudha PoobalanLALorna AucottTGTara Gurung

Key Result

Maternal obesity (BMI 30-35) more than doubled the odds of caesarean section compared to normal BMI (OR 2.26; 95% CI 2.04-2.51), with morbid obesity further increasing the risk (OR 3.38).

Study Design

Type

Meta-Analysis

Structured PICO

Does increasing maternal BMI increase the risk of elective and emergency caesarean delivery in nulliparous women?

P
Population
Nulliparous pregnant women (11 cohort studies)
I
Intervention
Overweight (BMI 25-30 kg/m²), obese (BMI 30-35 kg/m²), and morbidly obese (BMI > 35 kg/m²)
C
Comparator
Women with normal BMI (20-25 kg/m²)
O
Outcome
Elective and emergency caesarean delivery rateshard clinical

Increasing maternal BMI is strongly and dose-dependently associated with an increased risk of both elective and emergency caesarean delivery in nulliparous women.

Main Result

Effect estimate: OR 2.26 (95% CI 2.04-2.51)

Limitations

  • Only three of the 11 included cohort studies were prospective in nature

Abstract

The objective of the study was to investigate the association between increasing maternal body mass index (BMI) and elective/emergency caesarean delivery rates. Systematic review and meta-analysis of published cohort studies were used. The bibliographic databases, MEDLINE, EMBASE, CINAHL, were searched systematically, with no language restrictions, from 1996 to May 2007. MeSH terms and key words for 'pregnancy', 'obesity', 'overweight,''body mass index' and 'caesarean section' were combined with the Cochrane Collaboration strategy for identifying primary studies. Finally, 11 papers were considered eligible for inclusion in the review. Although all the papers were cohort studies, only three were prospective in nature. Compared with women with normal BMI (20-25 kg m(-2)), the crude pooled odds ratios (95% confidence intervals) for caesarean section in overweight (BMI 25-30 kg m(-2)), obese (BMI 30-35 kg m(-2)) and morbidly obese (BMI > 35 kg m(-2)) women were 1.53 (1.48, 1.58), 2.26 (2.04, 2.51) and 3.38 (2.49, 4.57) respectively. The pooled odds of having an emergency caesarean section were 1.64 (95% confidence intervals 1.55, 1.73) in overweight and 2.23 (2.07, 2.42) in obese women. Caesarean delivery risk is increased by 50% in overweight women and is more than double for obese women compared with women with normal BMI.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Poobalan et al. (2008) conducted a meta-analysis in Pregnancy in nulliparous women. Overweight and obesity (BMI > 25 kg/m2) vs. Normal BMI (20-25 kg/m2) was evaluated on Caesarean section (OR 2.26, 95% CI 2.04-2.51). Maternal obesity (BMI 30-35) more than doubled the odds of caesarean section compared to normal BMI (OR 2.26; 95% CI 2.04-2.51), with morbid obesity further increasing the risk (OR 3.38).

synapsesocial.com/papers/6a1ca3dd5a7763abe7898a94https://doi.org/10.1111/j.1467-789x.2008.00537.x
Ask AI
Helpful
Bookmark
Share
View Full Paper