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July 23, 2014BMJ109 citationsOpen Access

Dabigatran: how the drug company withheld important analyses

DCDavid D. Cohen

Structured PICO

Does monitoring drug plasma levels of dabigatran improve safety?

I
Intervention
Dabigatran (new generation oral anticoagulants)
O
Outcome
Safety improvement via monitoring drug plasma levelssafety

An investigation suggests that recommendations for dabigatran may be flawed because the manufacturer withheld evidence that monitoring plasma levels could improve safety.

Abstract

In an investigation by The BMJ Deborah Cohen finds that recommendations for use of new generation oral anticoagulants may be flawed because regulators did not see evidence showing that monitoring drug plasma levels could improve safety

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Cite This Study

David D. Cohen (2014) studied this question.

synapsesocial.com/papers/6a1d14e4feb402ac612f2152https://doi.org/10.1136/bmj.g4670
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